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Mendelian randomization supported causal associations between higher blood pressure and higher PSMD, and between elevated PSMD and increased stroke risk, particularly intracerebral hemorrhage

PC, pyruvate carboxylase

Mice deficient in the Fas or FasL signaling pathway (MRL lpr or gld/gld, respectively) develop lupus and Sjgren syndrome (SS)-like disease, and accumulate T cells in lacrimal glands, eyes, and conjunctiva 92,93,94