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It will be interesting to investigate whether persistent BCL-2 expression in AR cyto CRPC cells is caused by, in addition to the loss of AR-mediated BCL-2 repression, signaling functions of cytoplasmic AR and/or by other nuclear TFs such as NF-B, STAT33 and E2F1

Endodontic Topics (2002) 11

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1 This makes it difficult to perform activities that require skill and concentration, or where the safety of others is involved