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Vitamin B12 deficiency can cause fatigue, memory and cognitive loss, myalgias(leg and back pain), poor digestion, mood changes, hair loss, weight gain due to poor metabolism

Sermorelin relies on a functional pituitary gland

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Elevations in blood pressure (180 mmHg systolic or 110 mmHg diastolic) were observed in approximately 18% of healthy subjects (not exposed to cyanide) receiving hydroxocobalamin 5 g and 28% of subjects receiving 10 g

Proton pump inhibitors reduce gastric acid production, which impairs the release of food-bound B12 but has less effect on synthetic B12 in supplements