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For men, GH works alongside testosterone to boost muscle growth, endurance, and strength

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A successful pH-sensitive mutant would exhibit a K_D comparable to the wild-type antibody at neutral pH to ensure cell surface binding, but a significantly weakened K_D (markedly increased k_off rate) at acidic pH to facilitate rapid dissociation in the lysosome and enable efficient receptor recycling [76]

10, 11, all four NPCs express heparan sulfate proteoglycans (HSPG) syndecan-1 and syndecan-2 which are absent in HNC cells