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For research implications: if you want to study GH effects in isolation without the confounding effects of elevated cortisol (which is catabolic, immunosuppressive, and affects body composition) and prolactin Ipamorelin is the more appropriate tool

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higher doses show dose-dependent responses but may offer limited added benefit with routine use [4]

2020 Oct;8(9):3175-3177

Do not shake vigorously gentle swirling is preferred