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Skin barrier repair Commercial epidermal tissues EpiSkin (L'Oral Research and Innovation Center, Shanghai, China) is an in vitro reconstructed human epidermis (RHE) from normal human keratinocytes and is similar to the in vivo human epidermis

doi: 10.1016/j.tplants.2018.06.004 64 Rodriguez-PeaR.MounadiK

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A program without a target cannot be optimized through medicinal chemistry, cannot generate target-engagement biomarkers and cannot be de-risked for off-target liabilities