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Human data beyond a few months are limited

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Because previous studies have demonstrated that NAD + depletion can induce cellular senescence, while the senescence associate secretory phenotype (SASP) in turn can induce CD38 26,27 , it was important to examine the impact of Ab68 on p21, a widely used albeit non-specific marker of cellular senescence

Neuroprotection and Mental Resilience Animal studies suggest DSIP may protect against neurodegeneration and oxidative stress May improve cognitive flexibility under sleep deprivation 5