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Description

doi: 10.1074/jbc.M113.458141

Bulletin of Experimental Biology and Medicine, 131(3), 285292

The cation resin is responsible for capturing positive ions (cations)such as calcium, magnesium, and sodiumpresent in the water, exchanging them for hydrogen ions

It activates GHS-R1a and CD36 receptors in cardiac tissue, with CD36 playing a key role in providing the myocardium with its major energy substrate, and agonistic CD36 binding protecting against myocardial damage and dysfunction by ischaemia/reperfusion with mice deficient for CD36 showing complete loss of GHRP-6-mediated cardioprotection, confirming CD36 as an essential receptor for its cardiac effects