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Horm Metab Res 33 : 156162 Scavo LM et al

Reduced calorie diet combined with NNMT inhibition establishes a metabolic memory

Compared to antimuscarinic drugs, mirabegron was less frequently associated with urinary retention, constipation, cognitive impairment and dry mouth and may be therefore considered as an alternative for patients in whom antimuscarinics are contraindicated, not tolerated [81, 115, 223] or did not sufficiently improve incontinence symptoms [55]

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The recommended daily intake of niacin for lactation is ~17-20 mg, which is easily met by a normal diet