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Deficiency in vitamin B6 is commonly linked to malnutrition, alcoholism, malabsorption syndromes, or as an adverse effect of certain medications, such as cyclosporine, hydralazine, cycloserine, penicillamine, isoniazid, levodopa, phenelzine and chemotherapy treatments ( Pyridoxine is crucial for the biochemistry of the nervous system, playing a significant role in amino acid biosynthesis and degradation (57, 58)

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Reported exposure included healthy volunteers and small groups with ulcerative colitis, knee pain or interstitial cystitis

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