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10.1016/S0140-6736(16)00141-0 123 KamphorstJ

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For example, an in vitro study reported that Flu can induce resistance to multiple antibiotics in Escherichia coli via reactive oxygen species-mediated mutagenesis 79

After ultracentrifugation at 200,000 g for 20 min at 4 C the resulting supernatants were used in the assays