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Thus, the interactive metabolic effects of high folatelow vitamin B-12 may occur at levels of exposure to folic acid that are regularly achieved in populations consuming folic-acidfortified foods and supplements

Symptoms of Vitamin B12 Overdose Dermatological Symptoms: Acne and Facial Ruddiness One of the documented symptoms of vitamin B12 overdose is the development of acne

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Based on recent evidence, we propose an algorithm illustrating a screening and diagnostic strategy for vitamin B12 deficiency in patients with T2D on metformin therapy (Figure 1)

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