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Description

The m6A modification-related gene RBM15, which is highly expressed in AD samples, enhances glycolysis of macrophage, and affects polarization by promoting M1-type and decreasing M2-type markers

Sasaki et al., 2019

In vitro studies revealed that diminishing NNMT expression via RNA interference (RNAi) and inhibiting NNMT with MNAM substantially augmented oxygen consumption (OC) in adipocytes