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Pinna A, Ragaisyte I, Morton W, Angioletti-Uberti S, Proust A, DAntuono R, Luk CH, Gutierrez MG, Cerrone M, Wilkinson KA, Mohammed AA, McGilvery CM, Surez-Bonnet A, Zimmerman M, Gengenbacher M, Wilkinson RJ, Porter AE

ROS, due to unpaired electrons, have strong oxidative potential and can damage cellular DNA and proteins (Guo et al

Some peptides with prominent antimicrobial potencies under low-salt conditions lose their activities at physiological salt conditions and/or in serum (due to interactions with serum proteins)

Although AVE significantly alleviated MMS-induced toxicity, some residual damage persisted, suggesting that it cannot completely counteract genotoxic stress at the tested concentrations

175,176 STATs are phosphorylated and translocated into the nuclear compartment to transcriptionally upregulate specific genes, 177 often leading to cell proliferation or differentiation