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312,313 In a rat model of AP, plasma MCP-1 levels were significantly elevated as early as 6 h following pancreatic duct injection of sodium taurocholate, 314 suggesting that acinar-derived MCP-1 acts as an early inflammatory mediator in AP

Chronic zinc deficiency in mice disrupted T cell lymphopoiesis and erythropoiesis while B cell lymphopoiesis and myelopoiesis were maintained

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The Therapeutic Potential of NK-1R Antagonists in Inflammatory CNS Disorders The involvement of tachykinins in a wide range of pathological processes has made them an attractive target for therapeutic intervention, and the pharmaceutical industry has initiated the development of additional NK-1R antagonists (as discussed in Quartara and Altamura, 2006

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