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To trigger necrotic cell death, Mtb used focal adhesion kinase (FAK) in a time-dependent manner, first by exploiting RIPK1 and then, to a lesser extent, by using RIPK3-MLKL, to produce ROS ( 5.1.5 Pyroptosis Additionally, Mtb escape host clearance involves pyroptosis control

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This leads to the decrease in catalase activity [52]

CircACC1 regulates assembly and activation of AMPK complex under metabolic stress