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Disease-associated mutant ubiquitin causes proteasomal impairment and enhances the toxicity of protein aggregates

Pharmacokinetic and toxicokinetics data including children-, pregnancy-, geriatric-, and obesity-related data Adult N-Acetylcysteine was given intravenously and as three fast dissolving and one slow-release formulation, on separate occasions, as a single dose of 600 mg to 10 fasting (5 men and 5 women) healthy volunteers

Robb et al., 2015

The molecular and metabolic landscape of iron and ferroptosis in cardiovascular disease

Most recently, the high abundance of a delta GST, SzeaGSTd1 in Sitophilus zeamais antennae, inhibition of SzeaGSTd1 catalytic activity by capryl alcohol, along with the degradation of capryl alcohol by recombinant SzeaGSTd1 were observed [110]