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A: In vitro studies involve cells in a controlled environment, using molar concentrations (M), while in vivo studies involve whole organisms and use weight-based dosages (mg/kg)

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Clinicians should discontinue amiodarone at the first sign of hepatic injury, including jaundice, ascites, hepatomegaly, or aminotransferase levels exceeding five times the upper limit of normal (11)(68)

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