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In a randomized clinical trial on patients with diabetic nephropathy accompanying chronic kidney disease, following NSO treatment, there was a significant reduction in blood glucose, serum creatinine, blood urea, and 24 h total urinary protein levels and an increase in glomerular filtration rate, 24 h total urinary volume, and hemoglobin level [140]

However, the problem is the poor reproducibility of quantitative methods, and therefore the application of oxLDL as a marker of oxidative stress in the prediction of cardiovascular diseases is doubtful

AgathocleousMMeachamCBurgessRPiskounovaEZhaoZCraneGet alAscorbate regulates haematopoietic stem cell function and leukaemogenesis

doi:10.1016/j.ejphar.2021.174253 245

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