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The long term outcomes for recipients of deceased donor liver transplants showed graft failure rates of 15.0% at 3 years for transplants done in 2018, 20.7% at 5 years for transplants done in 2016, and 38.5% at 10 years for transplants done in 2011

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Although some patients may lack primary redox dysregulation, any point of entry (NMDA receptor hypofunction, neuroinflammation, or dopamine dysregulation) can favor oxidative stress, which may be a common consequence of distinct etiologies (see review by Steullet et al