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doi: 10.1007/s00109-013-1069-2 209 MittelstadtPRMonteiroJPAshwellJD

J Med Chem2026 Mar 12;69(5):5501-5539

Postmenopausal symptoms may continue for years, especially if hormone levels remain low and changes (e.g., bone density, cardiovascular risks) begin to emerge

1.2.2.5.2) Synthesis of stereopure INT2-S and INT2-R compounds tert-butyl (2-(4-((S)-2-((((9H-fluoren-9- yl)methoxy)carbonyl)amino)propanamido)phenyl)-2-hydroxyethyl)carbamate was dissolved in 5 mL of DMF/piperidine 9:1 (v/v) and stirred 15 min at room temperature