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Adenosine Production by Canonical and Alternative Ectoenzymatic Pathways The purinome exploits the metabolically reprogrammed niche to generate extracellular ADO which is locally produced by the multicellular network (Figure 2)

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These are typified by the following two enzymes: Methylmalonyl-CoA mutase [edit] Methylmalonyl coenzyme A mutase (MUT) is an isomerase enzyme that uses the AdoB 12 form and reaction type 1 to convert L-methylmalonyl-CoA to succinyl-CoA, an important step in the catabolic breakdown of some amino acids into succinyl-CoA, which then enters energy production via the citric acid cycle

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