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Disclosures: Rodolphe SOBESKY: Orphalan: Consultant, AbbVie: Consultant, Christophe Desterke: Nothing to Disclose, Aurelia Poujois: Nothing to Disclose, Eleonora De Martin: Nothing to Disclose, Ilias Kounis: Nothing to Disclose, Cyrille Feray: Nothing to Disclose, Jean-Charles Duclos-Vallee: Nothing to Disclose, Audrey Coilly: Nothing to Disclose 2533 CLINICAL AND LABORATORY PROFILE OF ADULT PATIENTS WITH IDIOPATHIC CHOLESTATIC LIVER DISEASE ACCORDINGTO THE PRESENCE OF MDR3 MUTATIONS Paulo Bittencourt 1 Vivian Rotman 2 Lvia Geovana Celestino 3 Antonio Ricardo Andrade 4 Liana Codes 5 Raimundo Gama 3 Raymundo Parana 6 Larissa Athayde Costa 7 Maria Ferraz 3 Gilda Porta 8 , 1 Bahiana School of Medicine and Public Health, 2 Federal University of Rio de Janeiro, 3 Federal University of Sao Paulo, 4 Federal University of Bahia, 5 Portuguese Hospital of Salvador, Bahia, 6 Instituto D'Or de Pesquisa e Ensino, 7 Mendelics Analise Genomica, 8 University of Sao Paulo School of Medicine Background: In adult patients, MDR3 deficiency has been recognized after genetic testing in up to a third of the subjects with cholestatic liver disease (CLD) of unknown cause

Arch Toxicol 88: 17731786, 2014

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Type beta transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts