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Whether liver-specific GSH synthesis was responsible for downregulated lipogenic gene expression and reduced serum triglycerides or whether these phenotypes were a byproduct of a liver-independent process in Gclc KO mice was unclear

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Due to the limited number of studies on KD in PD patients, this section also considers side effects observed in research on other populations

Finally, GSH availability negatively regulates SLC25A39 protein abundance, coupling redox homeostasis to mitochondrial GSH import in mammalian cells

Reconstituted GHK-Cu only remains stable for 21-30 days refrigerated due to copper oxidation concerns