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Studies have demonstrated that intestinal decontamination with polymyxin B and neomycin significantly reduces levels of LPS, aspartate aminotransferase (AST), and liver histopathological scores in male Wistar rats that were given alcohol via gavage for 3 weeks [190]

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Interestingly, this group was also more likely to have hypertension, higher BMI, and higher ELF score at baseline and less likely to have Type 2 diabetes mellitus

It targets the vagus nerve via the cholinergic pathway

In addition, patients are usually given oral antivirals as prophylaxis to prevent spontaneous recurrence of epithelial disease while the patient is on steroids