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The supernatants were transferred to new tubes and stored until use at -20C

Health status considerations: Generally healthy adults with physician clearance, individuals without contraindications (pregnancy, active malignancy, severe organ disease), those willing to commit to proper administration protocols and monitoring, and patients who understand the research-purposes-only status and informed consent requirements

TB-500 has also been studied for anti-inflammatory properties and angiogenic effects

The primary endpoint was the percentage change in body weight from baseline to week 26

Upregulation of BDNF mRNA expression in the barrel cortex of adult mice after sensory stimulation