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483 Coinhibition of the proteasome and Nrf2 can overcome proteasome inhibitor resistance by blocking the Nrf2-mediated antioxidant defense activated upon proteasome inhibition

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Nat Chem Biol 4:278286 Winterbourn CC, Hampton MB (2008) Thiol chemistry and specificity in redox signaling

TNF- inhibitors have also shown antidepressant properties [338], so they have also been proposed as a potential treatment in BD with contradictory and unsatisfactory results [339]