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SIRT1s ability to deacetylate and thereby activate key proteins involved in ferroptosis, such as GPX4 and FOXO3A, positions it as a nodal point in the regulation of this cell death process

In addition, the nongenetic surface modification of MSCs with sialyl Lewis X carbohydrate using a polyacrylamide linker and biotin/streptavidin interaction showed robust rolling on the endothelium and homed inflamed tissues in vivo more efficiently than unlabeled MSCs 46