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BALB/c mice subcutaneously inoculated with A549 cells, oral gavage of 40 mg/kg lovastatin combined with intraperitoneal administration of 200 g per dose of PD-L1 antibody resulted in downregulation of GPX4 expression and increased lipid peroxidation levels in the tumor tissue

Metabolites with q -values greater than 0.05 are considered exploratory, aiming to identify potential changing trends and to generate hypotheses for subsequent research

Discussion Despite the urgent need for more effective therapies against H

This effect reflects increased amino acid uptake, increased protein synthesis and decreased oxidation of proteins

ATP was measured using a luciferin-luciferase kit, and chemiluminescence at 560 nm was detected using a microplate luminescence analyzer