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CPTAC proteomic data analysis For proteomic analysis of human brain and GBM tissues, raw phosphoproteome and proteome mass spectra converted to .mzML open standard format from the Clinical Proteomic Tumour Analysis Consortium (CPTAC) GBM discovery cohort were downloaded from the Proteomic Data Commons ( study IDs PDC000204 and PDC000205, RRID: SCR_018273)

Subtle variations in PTEN dose determine cancer susceptibility

[DOI] [PMC free article] [PubMed] [Google Scholar] 139.Datsi A., Sorg R.V

In vivo studies suggested it to be resulting from oscillations of inhibition and excitatory thalamic and corticothalamic neurons, which in turn, initiate Grand Mal epilepsy [80]

This approach has the potential to enhance the sensitivity and specificity of CRC profiling (203)