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Principal component analysis (PCA), metabolic pathway enrichment analysis, and Venn diagram generation were accomplished using the Origin 2019 software (OriginLab Corporation, Northampton, MA)

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An inducible Clec7a-CreERT2 mouse line enables selective genetic tracing of proliferative-region-associated microglia (PAM) and DAM in the CNS ( in vivo tracing demonstrated state transitions, exhibiting reversible microglial plasticity