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We recently demonstrated that in HEK293 cells over-expressing IGF-1 isoforms the proIGF-1s are the main forms produced intracellularly, and for proIGF-1Ea both unglycosylated (~12 kDa) and glycosylated (~17 kDa) forms were detected 7

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The science behind this pairing is not complicated once you understand how each compound works independently, and this guide breaks down everything you need to know about combining them safely, timing your doses correctly, and understanding what realistic results actually look like