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In the United States alone, the economic burden of PD exceeded $52 billion in 2020, with caregivers losing an average of $19,000 in annual income due to reduced work hours or job loss (Chaudhuri et al., 2024)

Studies say that the total amount of Zinc in all body fluids and tissues has been recorded to almost 60%

However, how ATF4 functions in response to these distinct modes of regulation and its broader role as a downstream target of mTORC1 are unknown

Conclusion This systematic review revealed NAC as a promising intervention compound to alleviate oxidative stress and improve clinical outcomes in PD

Van Ameringen M, Patterson B, Simpson W, Turna J