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Our data suggest that hypermethylation of the 25-hydroxylases, 1--hydroxylase enzymes, and the vitamin D receptor promoter, accompanied by hypomethylation of CYP24A1, leads to impaired expression and possibly a predisposition to VD deficiency/inadequacy

Loeber, G., Dworkin, M

6 Clinical relevance and translational potential of mtDNA monitoring The growing understanding of mtDNAs role in HIV pathogenesis and ART-related toxicity has stimulated interest in its value as a clinically actionable biomarker

For example, a study that relied solely on mass spectrometry analysis proposed that a myriad of different RNA modifications decorate viral RNA genomes, including m 1 A in human immunodeficiency virus type 1 (HIV-1) 63

Sheteiwy MS, Shao H, Qi W, Daly P, Sharma A, Shaghaleh H, et al