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These results demonstrate that TGF--induced transition from fibroblasts to myofibroblasts involves canonical TGF-/Smad2/3 signaling, non-canonical TGF-/ERK1/2 signaling, and ROS production via NAD(P)H oxidase

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doi: 10.1038/ejcn.2010.222 23 GutiErrez-GrijalvaEPAmbriz-PereDLLeyva-LopezNCastillo-LopezRIHeiediaJB