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Notably, this study is the first to confirm the critical role of the ROS/mTOR/HIF-1 axis in regulating neutrophil metabolism in psoriasis and to elucidate its mechanistic contribution to NETs formation and inflammation

10.1016/j.ab.2019.113476 146 Sumanth KumarD.Jai KumarB.MaheshH

Wang Q, Hardie RA, Hoy AJ, van Geldermalsen M, Gao D, Fazli L, Sadowski MC, Balaban S, Schreuder M, Nagarajah R, Wong JJ, Metierre C, Pinello N, Otte NJ, Lehman ML, Gleave M, Nelson CC, Bailey CG, Ritchie W, Rasko JE, Holst J (2015) Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development

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