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Effects of omega-3 and6 polyunsaturated fatty acids on ovine follicular cell steroidogenesis, embryo development and molecular markers of fatty acid metabolism

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Consistent with reports showing that the topoisomerase II-inhibitor Etoposide is a substrate of ABCC1 42 , the GI 50 of MOLM-13 ABCC1 -knockout clones to Etoposide was 1.4 2.4-fold lower than in control cells (Supplementary Fig