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Behav Brain Res 140:147 Romero A, Hernndez L, Garca-Nogales P, Puig MM (2010) Deletion of the inducible nitric oxide synthase gene reduces peripheral morphine tolerance in a mouse model of chronic inflammation

Disrupting this interaction by substituting E134 and D137 in BubR1 with positively charged residues individually or combinatorially had no effect on kinetochore localization, but almost completely abolished SAC signaling, a phenotype similarly observed when replacing Cdc20 R286 with a negatively charged residue (Supplementary Fig

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Even after changing food choices and other steps, some people with TMAU believe they still need to keep life at arms length

In this section, we summarize how metabolic interventions sensitize cancer cells to these therapies, offering a potential avenue for combination therapy