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doi: 10.1038/s41397-019-0119-8

on the one hand, inhibition of Nrf2 can cause ferroptosis in tumor cells, and on the other hand, activation of Nrf2 can also set off ferroptosis in tumor cells

doi: 10.3389/fmicb.2013.00263 94 BayarriMAMilaraJEstornutCCortijoJ

Through this comprehensive integration, we critically evaluated current strategies, identified emergent design paradigms, and categorized the most pressing translational challenges, offering a refined understanding essential for accelerating the clinical development of brain-targeted nano-phytochemicals