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Furthermore, given that the effects of 5-HT 2C agonists also include weight loss and a reduction in reward-seeking behaviors, the use of compounds that enhance 5-HT 2C signaling would also be clinically relevant for the treatment of obesity or to prevent relapse to drug abuse

Otterson GA, Villalona-Calero MA, Hicks W, Pan X, Ellerton JA, Gettinger SN, et al

These include the dopamine 1 receptor (D1R), the dopamine 2 receptor (D2R), the melanocortin-3 receptor (MC3R), the serotonin 2C receptor (5-HT 2C ), and possibly the cannabinoid type 1 receptor (CB1)