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This affective dysregulation has been associated with reality distortion [159] and projection of negative meaning to neutral stimuli, resulting in disproportional reactivity to minor daily stressors and maladaptive evaluation of external reality in susceptible vulnerable individuals [16, 160, 162]

Despite this reduction, mitochondria in HuR Hep-/- hepatocytes displayed a more circular morphology, as quantified by the circularity index (4 area/perimeter

However, in neurodegenerative diseases, the extent and functional relevance of such reactivation remain ambiguous

DIO mice were divided into four groups such that each group had the same average mean body weight ( n = 8 mice), and their movements were recorded for a period of 20 min