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The IL-22-responsive transcriptional module is significantly enriched in both mouse colitis models and human UC, with elevated levels of neutrophil-active chemokines such as Cxcl1 , Cxcl2 , Cxcl3 , and Cxcl5 [94]

This mixed plasmid DNA was used as template for a second cycle of error-prone PCR and FACS as described above

Following the success of SLE, clinical research has extended the use of anti-CD19 CAR T-cell therapy to other autoimmune conditions, such as systemic sclerosis (101103), refractory immune-mediated necrotizing myopathy (103), refractory anti-synthetase syndrome (104, 105), and myasthenia gravis (96)

Furthermore, the high-dose CHIE increased the enzyme activity of TrxR (Figure 5K) in the liver

370 In HCC, CDKN2A promotes tumor cell proliferation and migration capabilities as well as attenuating cuproptosis