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Similar content being viewed by others Introduction The transcriptional coregulator and a core component of the Polycomb Repressive Deubiquitinase (PR-DUB) complex, ASXL1 (additional sex combs like 1), is frequently mutated and truncated in human malignances, particularly in acute and chronic myeloid leukemias (AML and CML, respectively) and myelodysplastic syndromes (MDS) 1,2,3,4,5,6,7 (Fig

Igarashi T, Kohara A, Shikata Y, Sagami F, Sonoda J, Horie T, et al

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Severe neurological symptoms warrant urgent treatment

As for GSHtot, the concentration of GSH was almost constant until the mid-log phase and then increased to reach its maximum value at 2022 h