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The TDP-43 NTD contains pS48 S/T phosphorylation, which has been detected in multiple phosphoproteomic analyses of various cell lines 85,86

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Very high doses without supervision may cause bloating or mild digestive discomfort Long-term mega-dosing offers no added benefit for most people Absorption tends to plateau beyond a certain point For the majority of adults, staying within 5001,000 mg per day delivers results without unnecessary strain

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