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They validated their findings with subsequent real-world data from Ontario and Connecticut

In most cases, these symptoms are mild to moderate and improve over time, but they can be severe enough for some patients to discontinue treatment (semaglutide STEP 1 trial results)

[5] [6] However, it is important to emphasise that not all mouth ulcers are caused by B12 deficiency , and other factors such as immune dysfunction, genetic predisposition, and local trauma also play important roles

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This condition can affect the roof of your mouth, tongue, gums, throat, and the inside of your cheeks. Its often accompanied by a bitter or metallic taste