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et al., 2012), visceral pain (Prochazkova et al., 2013

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The secretion of antimicrobial peptides by Paneth cells is regulated by susceptibility genes and depends on microbiota interactions [183], while the loss of transcription factor EB (TFEB) in colonic epithelium weakens the antioxidant barrier [184]

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The goal is the minimum effective dose, not the maximum tolerable dose

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