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Phase I metabolic enzymes are represented by the cytochrome P450 (CYP450) superfamily

Inhibition of endothelial CAM expression by natural compounds Endothelial activation and subsequent upregulation of cell adhesion molecules (CAMs) constitute a critical downstream event through which upstream inflammatory signaling is translated into leukocyte recruitment, microvascular dysfunction, and tissue injury in ischemic acute kidney injury (AKI)

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