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For example, it increases the abundance of Bacteroides and Prevotella while reducing Firmicutes and Actinobacteria [169, 170], essentially reversing the microbial imbalance typically observed in PD [133]

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This motif exerts a negative regulatory effect on the Akt/tuberous sclerosis complex (TSC)/mammalian target of the rapamycin (mTOR) pathway, thereby amplifying canonical autophagy (96)