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IL-1 is one of the most important pro-inflammatory factors, which can significantly upregulate the expressions of MMPs and accelerate cartilage degeneration under conditions of OA (Jenei-Lanzl et al., 2019)

C d villarama & H i maibach

Cel Biol 16 (9), 46044613

Patients with GPX4 overexpression had a reduced 5-year OS of 73% compared to 97% in patients with normal GPX4 expression (HR 2.95

60,61 The personalized and adaptive nature of TCM interventions, along with increasing evidence from pharmacological studies, supports their potential integration into gastroenterological practice