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Simultaneously, the mechanical properties of the ECM change significantly: the shear stiffness of the human nucleus pulposus increases from 12.5 kPa in Pfirrmann grade 116.5 kPa in grade V (Walter et al., 2017), collagen fibers thicken and become disorganized (Wuertz et al., 2007) (Table 1)

[3] You can use the dish soap you normally use to wash dishes or choose dish soap that's gentle on your hands

Beeswax's wax esters are derived primarily from palmitic and oleic acid (C16 and C18:1)